Hello Chris,
The part number KVR400X72RC3A/512 is ECC, registered memory. Your IS7-E motherboard is not compatible with ECC or ECC, registered memory. Please return this memory to the place of purchase for a refund. The correct memory for your system is unbuffered (non-registered), non-ECC memory. The Kingston part number for this is KVR400X64C3A/512.
If you have any other questions, please respond to this email with the email history so that we can help.
Best regards,
Brad Burnham
US Technical Support
Kingston Technology